DiHydroErgotAmine Nasal Spray
For The Relief Of Migraine Attacks
Introduction:
This formulae is presented by "U.S. Pharmacist" in the March 1993 issue. For a more complete discussion please refer to information found there. This medication has been used to abort and/or treat migraine or cluster headaches.
Formulae:
DiHydroErgotAmine Nasal Spray
| ..............Ingredient............... |
....Amt Each ml..... |
....Amt / 100mls.... |
| Dihydroergotamine Mesylate Powder |
2.5mg |
250mgs |
| Ethyl Alcohol 95% |
0.016mls |
1.6mls |
| Glycerin |
0.1ml |
10.0mls |
| 1/2 Normal Preserved Saline |
qs 1ml |
qs 100mls |
.
Method Of Preparation:
Dissolve the Dihydroergotamine Mesylate in the alcohol then add the glycerin, add the 1/2 normal preserved saline slowly with constant stirring. Allow suspension to hydrate then place 5mls of suspension in metered dose nasal spray bottles. The metered dose spray bottle will supply 100mg of suspension that contains
250mcg of Dihydroergotamine Mesylate. Dosage would be 4 sprays nasally every hour upto 12 sprays (3mgs) in 24 hours.
Source Of Medicinals:
Disclaimer:
The information above is provided for informational purposes only. It
is intented for the health care professional. It is the health care professional's
responsiblity to determine the usefulness of this information.
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