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Sophie's Once over Medical Checkup - Diagnosis: Cushings Disease
 

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THE ONCE OVER MEDICAL CHECKUP

March 01, 1998
As is customary with a new pet with an unknown background, we took Sophie to our Vet and had them do a once over examination.    The vet estimated Sophie's age as 5 - 7 years old, based on her physical appearance, teeth and eye condition.  On close examination, a long foxtail was found and extracted from the wound near one leg.  A couple more were fished out of her ears.  Then came the usual innoculations, and drawing of blood for heartworm and other tests.  She was indeed overweight - weighing in at 60 lbs!! She also seemed to pant a lot.  We speculated that this might be a by-product of her overweight condition. However, the vet postulated that there might be another reason - the dog may have Cushing's Disease.

Cushing's Syndrome is a hormonal disease in which the adrenal glands become overactive and secrete too much hormone.  Naturally occurring Cushing's (that not occurring from overuse of cortisone-type medications) is usually caused either by an overactive pituitary gland signaling the adrenal glands to work harder than they should, or by a hormone secreting tumor of the adrenal gland. The cause of the overactive pituitary gland is usually unknown. Cushing's Syndrome (also called hyperadrenocorticism) is a disease of humans and dogs and rarely of cats.

The "classic" symptoms of Cushing's syndrome are:

  • excessive thirst
  • excessive urination
  • increased appetite
  • abdominal enlargement (bloated abdomen)
  • muscle weakness
  • increased panting
  • lethargy
  • obesity
  • hair loss
  • skin infections
  • hyperpigmentation (age spots).
Not all patients with Cushing's will show all of these symptoms. Cushing's is often a slowly progressing disease and in many cases it will be suspected, tested for, and diagnosed before the signs become severe.
 
March 04, 1998
Besides the first blood test, two additional tests were performed.  This second test was performed to positively confirm the presence of Cushing's Syndrome.  Lab results were received in about 3-4 days and the results were positive.

March 09, 1998
At this point, we had the option to begin treatment with Lysodren.  This is a chemotherapy-type drug, that has demonstrated some negative side-effects, as reported by pet owners on the Internet.  To have the full range of options, it was necessary to determine the specific cause of the disease - whether related to the adrenal gland, or the pituitary gland.  The third blood test was performed to identify the pituitary gland as the cause.  The lab processing of the results took approximately a week and was positive. 

Next - Treatment for Cushing's Syndrome


Cushings Disease Definition | Cushing's Pet Forum

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  Author:   Vern Tallman, Santa Clara, CA  
Revised: September 1, 2000